Bioimaging
BIOIMAGING
Director: Xinmai Yang, Ph.D.
Bioimaging science is an evolving field of biomedicine and bioengineering that involves the development and application of imaging technologies and computational software tools to answer biological questions in life sciences. This discipline brings together engineers, computer scientists, physicists, biologists, chemists and clinicians engaged in the development of equipment and methodologies for characterizing tissue properties and examining its structure and function through in vivo or ex vivo visualization at multiple resolutions, ranging from molecular and cellular to organ level. The imaging technologies are mainly based on the principles of optics, photonics, magnetic resonance, nuclear medicine, radiation, ultrasonics and spectroscopy. Modern applications of bioimaging include multi-photon imaging, image-guided interventional procedures, surgical planning, oncology treatment planning, endoscopic and laparoscopic surgeries and virtual telemedicine. Image processing and analysis is an important part of bioimaging and allows measurement and quantification of anatomical, physiological and/or clinically meaningful parameters. This track is closely linked to the other tracks of the bioengineering program because of supplying critical supportive data. For example, as part of bioimaging, gene-array imaging and analysis provide data for mining with the techniques used in bioinformatics.
As the students in this track are prepared for careers in industry, academia and public service, they are trained in the current bioimaging modalities; fundamentals of physical and mathematical principles and operations, hardware and software, image contrast produced and its interpretation, image quality analysis and measures, quality control tests with phantoms, receiver operating characteristics and target detectability, molecular and cellular contrast agents. Students are exposed to in vivo and ex vivo applications and learn biomarkers specific to individual modality and their utilities. Students use this knowledge to interpret the image contrast for understanding the basic anatomical and physiological relationships in normal and abnormal (e.g. disease) states and for accurate and reproducible clinical diagnosis or visualization.
Track Faculty
- Professor, Chemical and Petroleum Engineering
- Professor, Pharmaceutical Chemistry
Associated Tracks
Bioimaging
Biomaterials & Tissue Engineering
Biomedical Product Design & Development
Biomolecular Engineering
Research Interests
Nanoparticles and Colloids in Pharmaceuticals and Biomedicine
Titles
Director, Hoglund Brain Imaging Center
Professor, Neurology
Associated Tracks
Bioimaging
Research Interests
Imaging Studies in Cognitive Recovery from Brain Injury and Stroke
Titles
Professor, Neurology
Associate Director, Alzheimer's Disease Center
Associated Tracks
Bioimaging
Research Interests
Utilizing MRI to examine how lifestyle factors such as exercise and diet influence brain aging and Alzheimer's
Titles
Professor, Neurology
Associated Tracks
Bioimaging
Research Interests
Developing neuroimaging (magnetic resonance spectroscopy and imaging) and signal processing methods to study brain bioenergetics and metabolic changes with aging and neurodegeneration in clinical and preclinical studies.
Titles
Associate Professor, Anatomy and Cell Biology
Associated Tracks
Bioimaging
Research Interests
Vasculogenesis
Tissue Movements During Early Development
Extracellular Matrix Assembly
Multicellular Motility
Associated Tracks
Bioimaging
Biomaterials & Tissue Engineering
Biomechanics & Neural Engineering
Biomedical Product Design & Development
Research Interests
Tissue Mechanics
Computational Joint Mechanics
Titles
Research Assistant Professor, Neurology
Associated Tracks
Bioimaging
Research Interests
Use of sophisticated signal processing of electrophysiologic cardiac signals to understand fetal autonomic nervous system development (fetal imprinting) and infant visual development
Titles
Professor, Electrical Engineering & Computer Science
Associated Tracks
Bioimaging
Biomedical Product Design & Development
Research Interests
Optical/RF Measurement and Bioscensors
Novel Photonic Devices
Optical Communication Systems
Titles
Associate Professor, Molecular and Integrative Physiology
Associated Tracks
Bioimaging
Research Interests
In vivo characterization of neurodegenerative diseases using novel MRI techniques
Titles
Professor, Anatomy and Cell Biology
Associated Tracks
Bioimaging
Research Interests
Computational analysis of cell and tissue dynamics during early embryogenesis, the Cell Biology of Vascular Pattern Formation, Physical Mechanisms of Morphogenesis, Cell Surface-Extracellular Matrix Interactions, Developmental Malformations
Titles
Professor, Civil, Environmental and Architectural Engineering
Associated Tracks
Bioimaging
Biomaterials & Tissue Engineering
Biomechanics & Neural Engineering
Biomedical Product Design & Development
Research Interests
Nano-micro-macro mechanics of calcified and soft tissues, constitutive modeling and computational methods, scanning acoustic microscopy and ultrasonic testing
Titles
Director, Stereotactic and Functional Neurosurgery Program
Vice Chair Education, Neurosurgery
Associate Professor, Neurosurgery
Associated Tracks
Bioimaging
Research Interests
Deep Brain Stimulation (DBS)
Titles
Professor & Vice Chair of Research, Department of Rehabilitation Medicine
Director, Landon Center on Aging
Associated Tracks
Bioimaging
Biomechanics & Neural Engineering
Biomedical Product Design & Development
Research Interests
Neural Mechanisms of Recovery after Brain Injury
implantable Devices for Brain Plasticity
Titles
Associate Professor, Anatomy and Cell Biology
Associated Tracks
Bioimaging
Research Interests
"Research in the lab is interdisciplinary and focuses on the dynamic nature of the extracellular matrix, the milieu that surrounds the cells, and contributes to their shape, locomotion, gene expression, and every aspect of their behavior...To study these dynamic molecules we use automated microscopes and fluorescent probes to perform time-lapse imaging of avian developmental events and the role of the ECM in these events."
Titles
Professor, Pharmacology and Toxicology and Neuroscience Graduate Program/Director, Microscopy and Analytical Imaging Resource Core Lab
Associated Tracks
BioImaging
Research Interests
The development and application of tools and workflows for multi-scale multi-modal correlated volume microscopies and three-dimensional volume reconstruction to unravel synaptic geometry
Titles
Assistant Professor, Director of Basic Research
Associated Tracks
Biomechanics & Neural Engineering
Computational Bioengineering
Bioimaging
Research Interests
Neural encoding of hand and finger movements
Brain-machine interfaces
Data science/machine learning for neurotechnologies
Titles
Professor, Director of Clinical Research
Associated Tracks
Bioimaging; Computational Bioengineering
Research Interests
Rehabilitation Medicine
- Track Director, Computational Bioengineering
- Associate Professor, Electrical Eng. and Computer Sci.
Associated Tracks
Bioimaging
Computational Bioengineering
Biomechanics & Neural Engineering
Biomedical Product Design & Development
Research Interests
Computational Medicine
Computational Surgery
Computational Anatomy
Computational Biomechanics
Patient-Specific Model and Mesh Generation
Image Processing
Titles
Professor, Pharmaceutical Chemistry
Associated Tracks
Bioimaging
Biomolecular Engineering
Research Interests
Utilizing cell adhesion molecules for targeted drug delivery and tissue engineering
- Director, Institute for Bioengineering Research
- Deane E. Ackers Distinguished Professor, Mech. Eng.
Associated Tracks
Bioimaging
Biomaterials & Tissue Engineering
Biomedical Product Design & Development
Research Interests
Professor Spencer and her research team are designing, synthesizing, and developing novel biomaterials for the repair and replacement of mineralized tissues. Under in vivo conditions, failure of a repair or replacement generally begins at the biomaterial/tissue interface and thus, a key aspect of our work is understanding the fundamental phenomena that control biological interactions at material interfaces.
Titles
Director, Center for Computational Biology
Professor, Molecular Biosciences
Associated Tracks
Bioinformatics
Research Interests
Development of molecular recognition methods for structural genomics and bioinformatics
Titles
Professor and Chair, Cancer Biology
Associate Director for Basic Sciences
Associate Director for Education
Associated Tracks
Bioimaging
Computational Bioengineering
Biomolecular Engineering
Research Interests
Tumor progression, invasion, metastasis,
Titles
Professor, Molecular Bioscience
Associated Tracks
Biomaterials, Bioimaging
Research Interests
Drug discovery
Drug delivery
Cell biology/engineering
Genetic engineering
Nanotechnology
Associated Tracks
Bioimaging
Research Interests
Photoacoustic Imaging
Biomedical Ultrasound